anti- APPL1 antibody

Descripción

Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway.

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC, IP

observerd MW

80kd

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:2000 - 1:5000; IHC: 1:20 - 1:200; IP: 1:500 - 1:2000

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

APPL1

alias

APPL1, APPL, DIP13alpha, MODY14, adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

uniprot id

https://www.uniprot.org/uniprotkb/Q9UKG1

gene id

https://www.ncbi.nlm.nih.gov/gene/26060

note

This product is for research use only.

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