APOL2 antibody
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935106861
info@markelab.com
name
APOL2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00504
tested applications
ELISA, WB, IHC
Description
May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | apolipoprotein L, 2 (APOL2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 37 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BQE5 |
| Gene ID | 23780 |
| Alias | APOL2, APOL-II, APOL3, apolipoprotein L2,APO L2 |
| Background | Antibody anti-APOL2 |
| Status | RUO |
| Note | Mol. Weight 37 kDa |
Descripción
Apolipoprotein L2 (APOL2) is another member of the Apolipoprotein L family and is involved in lipid metabolism, cellular transport, and immune responses. APOL2 is expressed in various tissues, including the brain, liver, and immune cells, and interacts with intracellular membranes and lipid-containing structures. While its function is less defined than APOL1, APOL2 is believed to participate in lipid transport and the regulation of cellular lipid balance. Recent research has suggested that APOL2 may play a role in the modulation of apoptosis, cellular survival, and responses to oxidative stress. Its expression levels are often altered in disease states such as cancers and neurodegenerative disorders, where APOL2 may contribute to tumor progression, inflammation, and immune regulation. Studies also suggest a connection between APOL2 and host-pathogen interactions, as its upregulation has been observed in response to infections and inflammatory cytokines. APOL2’s involvement in cellular homeostasis, combined with its emerging roles in immune response and lipid handling, makes it a promising target for further research into its function and potential therapeutic applications in cancer and immune-mediated diseases.
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