APOD antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
APOD antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00500
tested applications
ELISA, WB
Description
APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | apolipoprotein D (APOD) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1:5000-1:50000; IF: 1:50-1:500 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a |
| Clone ID | 7E10 |
| Observed MW | 30 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P05090 |
| Gene ID | 347 |
| Alias | APOD, Apod, apolipoprotein D |
| Background | Antibody anti-APOD |
| Status | RUO |
| Note | Mol. Weight 30 kDa |
Descripción
Apolipoprotein D (APOD) is a unique member of the apolipoprotein family, functioning as a lipid transporter in the plasma and extracellular fluids. Unlike other apolipoproteins, APOD is not synthesized in the liver but is predominantly produced in the central nervous system (CNS), liver, kidneys, and mammary glands. APOD associates with high-density lipoprotein (HDL) and contributes to cholesterol transport, as well as lipid metabolism. Structurally, APOD is classified as a member of the lipocalin family, which binds small hydrophobic molecules, such as arachidonic acid and cholesterol. It has a prominent role in antioxidant defense by neutralizing reactive oxygen species (ROS) and reducing oxidative stress, particularly in the CNS. APOD is upregulated during injury and neurodegenerative conditions, including Alzheimer’s disease, Parkinson’s disease, and stroke, indicating its neuroprotective function. Elevated levels of APOD are also found in cancer, cardiovascular disease, and diabetes, suggesting its role in cellular stress responses. APOD may regulate inflammation, cellular lipid homeostasis, and signal transduction, making it a promising biomarker and therapeutic target in age-related disorders, metabolic syndromes, and neurological diseases.
Related Products
Human APOD (Apolipoprotein D) ELISA Kit
Ver Producto
APOD antibody
APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.
Ver ProductoAPOD antibody
APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.
Ver Producto