API5 antibody
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935106861
info@markelab.com
name
API5 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00482
tested applications
ELISA, IHC, WB
Description
Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | apoptosis inhibitor 5 (API5) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 50-55 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BZZ5 |
| Gene ID | 8539 |
| Alias | Apoptosis inhibitor 5 (API-5),Antiapoptosis clone 11 protein (AAC-11),Cell migration-inducing gene 8 protein,Fibroblast growth factor 2-interacting factor (FIF),Protein XAGL,API5 |
| Background | Antibody anti-API5 |
| Status | RUO |
| Note | Mol. Weight 50-55 kDa |
Descripción
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