APH1A antibody

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935106861
info@markelab.com
name
APH1A antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00481
tested applications
ELISA, WB
Description
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP(beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | anterior pharynx defective 1 homolog A (APH1A) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:1000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 30 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96BI3 |
| Gene ID | 51107 |
| Alias | Gamma-secretase subunit APH-1A (APH-1a),Aph-1alpha,Presenilin-stabilization factor,APH1A,PSF |
| Background | Antibody anti-APH1A |
| Status | RUO |
| Note | Mol. Weight 30 kDa |
Descripción
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APH1A antibody
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP(beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
Ver Producto