AP3B2 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3(AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network(TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | adaptor-related protein complex 3, beta 2 subunit (AP3B2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:2000 IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 120-140 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB,IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q13367 |
| Gene ID | 8120 |
| Alias | AP-3 complex subunit beta-2,Adaptor protein complex AP-3 subunit beta-2,Adaptor-related protein complex 3 subunit beta-2,Beta-3B-adaptin,Clathrin assembly protein complex 3 beta-2 large chain,Neuron-specific vesicle coat protein beta-NAP,AP3B2 |
| Background | Antibody anti-AP3B2 |
| Status | RUO |
| Note | Mol. Weight 120-140 kDa |
Descripción
Related Products
AP3B2 antibody
Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3(AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network(TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Ver Producto
AP-3 Complex Subunit Beta-2 (AP3B2) Antibody
Adaptor protein-3 (AP3) is a heterotetrameric vesicle-coat protein complex. Some AP3 subunits are ubiquitously expressed, whereas others are expressed exclusively in neurons. The neuron-specific AP3 complex, which includes AP3B2, is thought to serve neuron-specific functions such as neurotransmitter release (Grabner et al., 2006 [PubMed 16788073]).
Ver Producto
AP-3 Complex Subunit Beta-2 (AP3B2) Antibody
AP3B2 Antibody is a Rabbit Polyclonal against AP3B2.
Ver Producto