ANXA2 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
ANXA2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00431
tested applications
ELISA, WB, IF, IHC, IP, FC
Description
Annexin A2(ANXA2), also named Annexin-2 or Lipocortin II, is a Ca2+ binding protein that is up-regulated in virally transformed cell lines and human tumors. This calcium-regulated membrane-binding protein, whose affinity for calcium is greatly enhanced by anionic phospholipids, may cross-link plasma membrane phospholipids with actin and the cytoskeleton and be involved with exocytosis. Heat-stress response may also involve Annexin-2.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | annexin A2 (ANXA2) |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500; IP:1:500-1:5000 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2b |
| Clone ID | 3E0 |
| Observed MW | 39 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IHC, IP, FC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P07355 |
| Alias | ANXA2,ANX2,ANX2L4,CAL1H |
| Background | Antibody anti-ANXA2 |
| Status | RUO |
| Note | Mol. Weight 39 kDa |
Descripción
ANXA7 is a calcium- and GTP-dependent membrane-binding protein that plays a key role in exocytosis, membrane repair, and cell signaling. It acts as a calcium sensor, facilitating the fusion of vesicles with the plasma membrane, particularly in processes such as neurotransmitter release and hormone secretion. ANXA7 is expressed in the brain, heart, and other tissues, where it contributes to cellular calcium homeostasis and cell survival mechanisms. Mutations or dysregulation of ANXA7 have been associated with neurodegenerative diseases, such as Parkinson's disease, and cancers, where it can act as a tumor suppressor by regulating cell proliferation and apoptosis. Its roles in membrane dynamics and calcium-dependent signaling underscore its importance in cellular communication and homeostasis.
Related Products
Human ANXA2 (Annexin A2) ELISA Kit
Ver Producto
Mouse ANXA2 (Annexin A2) ELISA Kit
Ver Producto