ANKRD50 antibody
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935106861
info@markelab.com
name
ANKRD50 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00415
tested applications
ELISA, WB, IP, IF
Description
Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1(PubMed:25278552).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ankyrin repeat domain 50 (ANKRD50) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:200-1:1000; IF: 1:20-1:200; IP: 1:200-1:1000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 156 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9ULJ7 |
| Gene ID | 57182 |
| Alias | ANKRD50,KIAA1223 |
| Background | Antibody anti-ANKRD50 |
| Status | RUO |
| Note | Mol. Weight 156 kDa |
Descripción
ANKRD50 is a protein with multiple ankyrin repeat domains that mediate protein-protein interactions and contribute to its role as a regulator of signaling pathways and cellular processes. ANKRD50 has been implicated in protein trafficking, where it may influence the localization and stability of key signaling proteins within the cell. It is believed to participate in endosomal transport, ensuring proper protein sorting and degradation. ANKRD50 may also play roles in transcriptional regulation and cellular stress responses, acting as a scaffold to coordinate signaling networks. Dysregulation of ANKRD50 has been linked to impaired cellular homeostasis and may contribute to diseases such as cancer and neurodegenerative disorders. Its role in protein localization and signaling highlights its importance in maintaining proper cellular function.
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