Ankyrin Repeat Domain 50 (ANKRD50) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Ankyrin Repeat Domain 50 (ANKRD50) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230415
tested applications
ELISA, WB, IF/ICC, IP
Description
ANKRD50 Antibody is a Rabbit Polyclonal against ANKRD50.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ankyrin Repeat Domain 50 (ANKRD50) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/200 - 1/1000, IF/ICC: 1/20 - 1/200, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC, IP |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9ULJ7 |
| Gene ID | 57182 |
| Alias | ANKRD50,KIAA1223 |
| Background | Antibody anti-ANKRD50 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
ANKRD50 is a protein with multiple ankyrin repeat domains that mediate protein-protein interactions and contribute to its role as a regulator of signaling pathways and cellular processes. ANKRD50 has been implicated in protein trafficking, where it may influence the localization and stability of key signaling proteins within the cell. It is believed to participate in endosomal transport, ensuring proper protein sorting and degradation. ANKRD50 may also play roles in transcriptional regulation and cellular stress responses, acting as a scaffold to coordinate signaling networks. Dysregulation of ANKRD50 has been linked to impaired cellular homeostasis and may contribute to diseases such as cancer and neurodegenerative disorders. Its role in protein localization and signaling highlights its importance in maintaining proper cellular function.
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