anti- ANKRD49 antibody

Este producto es parte de ANKRD - Ankyrin repeat domain
anti- ANKRD49 antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-ANKRD49

proveedor

FineTest

reference

FNab00414

Tested Applications

ELISA, WB, IF

reactivity

human,mouse

status

RUO

clonality

polyclonal

Descripción

Induces HBG1 expression(PubMed:16131492, PubMed:11162141). May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway(By similarity).


Background

ANKRD49 is a member of the ankyrin repeat protein family, characterized by its repeat domains that mediate protein-protein interactions in various biological processes. ANKRD49 is thought to play a role in nuclear functions, including chromatin organization and transcriptional regulation. It interacts with nuclear proteins and may regulate gene expression patterns that control cell growth, differentiation, and stress responses. Its function as a regulatory protein suggests a potential role in pathways that maintain genomic stability and cellular integrity. Dysregulation of ANKRD49 has been associated with developmental abnormalities and diseases where altered transcriptional activity contributes to pathogenesis, such as certain cancers.

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse


immunogen target

ankyrin repeat domain 49


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB, IF


observerd MW

27 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:200-1:2000; IF: 1:10-1:100


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

ANKRD49


alias

ANKRD49,FGIF,ANR49


note

This product is for research use only.


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