ANKRD49 antibody
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Name
ANKRD49 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab00414
Tested Applications
ELISA, WB, IF
Description
Induces HBG1 expression(PubMed:16131492, PubMed:11162141). May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway(By similarity).
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | ankyrin repeat domain 49 (ANKRD49) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:200-1:2000; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 27 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8WVL7 |
| Gene ID | 54851 |
| Alias | ANKRD49,FGIF,ANR49 |
| Background | Antibody anti-ANKRD49 |
| Status | RUO |
| Note | Mol. Weight 27 kDa |
Background
ANKRD49 is a member of the ankyrin repeat protein family, characterized by its repeat domains that mediate protein-protein interactions in various biological processes. ANKRD49 is thought to play a role in nuclear functions, including chromatin organization and transcriptional regulation. It interacts with nuclear proteins and may regulate gene expression patterns that control cell growth, differentiation, and stress responses. Its function as a regulatory protein suggests a potential role in pathways that maintain genomic stability and cellular integrity. Dysregulation of ANKRD49 has been associated with developmental abnormalities and diseases where altered transcriptional activity contributes to pathogenesis, such as certain cancers.
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