anti- ANKRD49 antibody
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Precio
Precio a consultar
Antibody anti-ANKRD49
proveedor
FineTestreference
FNab00414Tested Applications
ELISA, WB, IFreactivity
human,mousestatus
RUOclonality
polyclonalDescripción
Induces HBG1 expression(PubMed:16131492, PubMed:11162141). May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway(By similarity).
Background
ANKRD49 is a member of the ankyrin repeat protein family, characterized by its repeat domains that mediate protein-protein interactions in various biological processes. ANKRD49 is thought to play a role in nuclear functions, including chromatin organization and transcriptional regulation. It interacts with nuclear proteins and may regulate gene expression patterns that control cell growth, differentiation, and stress responses. Its function as a regulatory protein suggests a potential role in pathways that maintain genomic stability and cellular integrity. Dysregulation of ANKRD49 has been associated with developmental abnormalities and diseases where altered transcriptional activity contributes to pathogenesis, such as certain cancers.
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human,mouse
immunogen target
ankyrin repeat domain 49
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB, IF
observerd MW
27 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:200-1:2000; IF: 1:10-1:100
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
ANKRD49
alias
ANKRD49,FGIF,ANR49
uniprot id
note
This product is for research use only.
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anti- ANKRD49 antibody
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