ANKRD49 antibody

Este producto es parte de ANKRD - Ankyrin repeat domain
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935106861
info@markelab.com
name
ANKRD49 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00414
tested applications
ELISA, WB, IF

Description

Induces HBG1 expression(PubMed:16131492, PubMed:11162141). May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway(By similarity).

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
ankyrin repeat domain 49 (ANKRD49)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:200-1:2000; IF: 1:10-1:100
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
27 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q8WVL7
Gene ID
54851
Alias
ANKRD49,FGIF,ANR49
Background
Antibody anti-ANKRD49
Status
RUO
Note
Mol. Weight 27 kDa

Descripción

ANKRD49 is a member of the ankyrin repeat protein family, characterized by its repeat domains that mediate protein-protein interactions in various biological processes. ANKRD49 is thought to play a role in nuclear functions, including chromatin organization and transcriptional regulation. It interacts with nuclear proteins and may regulate gene expression patterns that control cell growth, differentiation, and stress responses. Its function as a regulatory protein suggests a potential role in pathways that maintain genomic stability and cellular integrity. Dysregulation of ANKRD49 has been associated with developmental abnormalities and diseases where altered transcriptional activity contributes to pathogenesis, such as certain cancers.

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