ANKRD26 antibody
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935106861
info@markelab.com
name
ANKRD26 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00411
tested applications
ELISA, IHC, IF, IP
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ankyrin repeat domain 26 (ANKRD26) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IP: 1:10-1:100; IHC: 1:20-1:200; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 196 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UPS8 |
| Gene ID | 22852 |
| Alias | ANKRD26,KIAA1074,THC2 |
| Background | Antibody anti-ANKRD26 |
| Status | RUO |
| Note | Mol. Weight 196 kDa |
ANKRD26 is a protein with ankyrin repeat domains that plays a role in hematopoiesis, the process of blood cell production. ANKRD26 is expressed in hematopoietic stem cells and progenitors, where it regulates cellular proliferation, differentiation, and survival. Mutations in ANKRD26 are associated with familial thrombocytopenia (THC2), a rare genetic disorder characterized by low platelet counts and an increased risk of myeloid malignancies such as acute myeloid leukemia (AML). ANKRD26 is believed to influence transcriptional regulation and cell signaling pathways that control blood cell development and homeostasis. Its dysregulation disrupts normal hematopoiesis, contributing to abnormal cell growth and blood disorders, making it a critical factor for maintaining proper hematopoietic function.
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