ANGPTL2 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
ANGPTL2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00397
tested applications
ELISA, WB, IHC, IP
Description
Induces sprouting in endothelial cells through an autocrine and paracrine action.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | angiopoietin-like 2 (ANGPTL2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000; IHC: 1:200-1:2000; IP: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 57 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UKU9 |
| Gene ID | 23452 |
| Alias | ARP2,HARP |
| Background | Antibody anti-ANGPTL2 |
| Status | RUO |
| Note | Mol. Weight 57 kDa |
Descripción
ANGPTL2 is a secreted glycoprotein that belongs to the angiopoietin-like (ANGPTL) protein family and plays critical roles in inflammation, angiogenesis, and tissue remodeling. ANGPTL2 promotes endothelial cell activation, migration, and vascular permeability, facilitating angiogenesis during wound healing and tissue repair. However, persistent overexpression of ANGPTL2 leads to chronic inflammation and tissue damage, contributing to the development of metabolic disorders, such as obesity and insulin resistance, as well as cardiovascular diseases. ANGPTL2 also enhances cancer progression by promoting tumor angiogenesis, metastasis, and epithelial-mesenchymal transition (EMT). Elevated ANGPTL2 levels are observed in various cancers, including breast, lung, and colorectal cancers, where its activity correlates with poor prognosis. It serves as a biomarker for inflammatory and tumor-associated conditions, linking inflammation to disease pathology. ANGPTL2’s dual role in tissue regeneration and chronic inflammation highlights its significance as a potential therapeutic target in cancer, cardiovascular diseases, and inflammatory disorders.
Related Products
Human ANGPTL2 (Angiopoietin-related protein 2) ELISA Kit
Ver Producto
Mouse ANGPTL2 (Angiopoietin Like Protein 2) ELISA Kit
Ver Producto