PRKAG1 antibody

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935106861
info@markelab.com
name
PRKAG1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab10337
tested applications
ELISA, WB

Description

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
35-40 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
UniProt ID
P54619
Gene ID
5571
Alias
5'-AMP-activated protein kinase subunit gamma-1 (AMPK gamma1, AMPK subunit gamma-1, AMPKg),PRKAG1
Background
Antibody anti-PRKAG1
Status
RUO
Note
Mol. Weight 35-40 kDa

Descripción

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