CRYAB antibody

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935106861
info@markelab.com
name
CRYAB antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00325
tested applications
ELISA, WB, IHC, IP

Description

Alpha B-crystallin, encoded by CRYAB gene, is multifunctional, serving as both a major structural protein in the lens and a small heat-shock protein in other tissues in mammals. Alpha B-crystallin may contribute to the transparency and refractive index of the lens. Single nucleotide polymorphisms(SNPs) in the promoter region of CRYAB gene have been associated with in multiple sclerosis. Mutations in the CRYAB gene cause distinct clinical phenotypes including isolated posterior polar cataract, myofibrillar myopathy, cardiomyopathy, or a multisystemic disorder combining all these features. Impairment of alpha-B crystallin dimerization may be relevant to the pathogenesis of these disorders.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
crystallin, alpha B (CRYAB)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:200-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
20 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P02511
Alias
Alpha-crystallin B chain,Alpha(B)-crystallin,Heat shock protein beta-5 (HspB5),Renal carcinoma antigen NY-REN-27,Rosenthal fiber component,CRYAB,CRYA2,HSPB5
Background
Antibody anti-CRYAB
Status
RUO
Note
Mol. Weight 20 kDa

Descripción

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