anti- ALDH3B2 antibody
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935106861
info@markelab.com
name
anti- ALDH3B2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00295
tested applications
ELISA, WB, IHC, IF
Description
Oxidizes medium and long chain aldehydes into non-toxic fatty acids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | aldehyde dehydrogenase 3 family, member B2 |
| Host | Rabbit |
| Reactivity | human,mouse,rat |
| Recommended Dilution | WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 43 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P48448 |
| Gene ID | 222 |
| Alias | ALDH3B2,ALDH8 |
| Background | Antibody anti-ALDH3B2 |
| Status | RUO |
| Note | This product is for research use only. |
Descripción
ALDH3B2 is closely related to ALDH3B1 and functions in detoxifying reactive aldehydes derived from lipid peroxidation and xenobiotic metabolism. ALDH3B2 is predominantly expressed in metabolically active tissues, where it protects cells from oxidative stress and aldehyde toxicity. It catalyzes the oxidation of formaldehyde, 4-HNE, and other toxic carbonyl compounds, playing a key role in cellular detoxification and maintaining redox balance. ALDH3B2 has been implicated in preventing DNA and protein damage caused by reactive aldehydes, thereby contributing to cellular protection in oxidative stress conditions. Dysregulation of ALDH3B2 may be associated with metabolic and degenerative disorders, as aldehyde accumulation can impair cellular function and promote inflammation. While its specific role in disease remains under investigation, ALDH3B2 is a potential therapeutic target for reducing aldehyde toxicity and improving cellular resilience to oxidative stress.
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