Aldehyde Dehydrogenase 3 Family Member B2 (ALDH3B2) Antibody
357.5€ (100 µg)
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Name
Aldehyde Dehydrogenase 3 Family Member B2 (ALDH3B2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx036264
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ALDH3B2 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Aldehyde Dehydrogenase 3 Family Member B2 (ALDH3B2) Immunogen: Recombinant fragment corresponding to 56-288 AA of human ALDH3B2. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 43 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ALDH3B2,ALDH8 |
| Background | Antibody anti-ALDH3B2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ALDH3B2 is closely related to ALDH3B1 and functions in detoxifying reactive aldehydes derived from lipid peroxidation and xenobiotic metabolism. ALDH3B2 is predominantly expressed in metabolically active tissues, where it protects cells from oxidative stress and aldehyde toxicity. It catalyzes the oxidation of formaldehyde, 4-HNE, and other toxic carbonyl compounds, playing a key role in cellular detoxification and maintaining redox balance. ALDH3B2 has been implicated in preventing DNA and protein damage caused by reactive aldehydes, thereby contributing to cellular protection in oxidative stress conditions. Dysregulation of ALDH3B2 may be associated with metabolic and degenerative disorders, as aldehyde accumulation can impair cellular function and promote inflammation. While its specific role in disease remains under investigation, ALDH3B2 is a potential therapeutic target for reducing aldehyde toxicity and improving cellular resilience to oxidative stress.
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