anti- Albumin antibody
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935106861
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Precio
Precio a consultar
Antibody anti-ALB
proveedor
FineTestreference
FNab00278Tested Applications
ELISA, WB, IHCreactivity
human,mouse,ratstatus
RUOclonality
polyclonalDescripción
This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor.
Background
Albumin or ALB, is a protein synthesized by the liver and is the most abundant protein in human blood plasma, comprising about 55% to 60% of total plasma protein by weight. It plays several critical roles: Osmotic regulation: Albumin contributes significantly to the oncotic pressure of blood, which helps maintain the balance of fluid distribution between the bloodstream and tissues. This osmotic pressure is crucial for preventing fluid leakage from blood vessels into surrounding tissues. Transportation: Albumin serves as a carrier protein, transporting various substances in the blood, including hormones, fatty acids, bilirubin, calcium, and drugs. By binding to these molecules, albumin helps solubilize them and transport them efficiently throughout the body. Buffering: Albumin acts as a buffer in the blood, helping to maintain pH balance by binding to acidic and basic compounds.Antioxidant: Albumin possesses antioxidant properties and plays a role in scavenging free radicals and protecting cells from oxidative damage.Because of its multiple functions, alterations in albumin levels can indicate various health conditions. Low albumin levels (hypoalbuminemia) can be seen in liver disease, kidney disease, malnutrition, inflammation, and certain chronic conditions. Conversely, high albumin levels (hyperalbuminemia) are less common but can occur in conditions such as dehydration or during recovery from burns.
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human,mouse,rat
immunogen target
albumin
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB, IHC
observerd MW
65 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:50 - 1:200; IHC: 1:50 - 1:500
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
or code
ALB
alias
GIG20,GIG42
uniprot id
note
This product is for research use only.
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