anti- Albumin antibody

Este producto es parte de ALB - Albumin
anti- Albumin antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-ALB

proveedor

FineTest

reference

FNab00278

Tested Applications

ELISA, WB, IHC

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor.


Background

Albumin or ALB, is a protein synthesized by the liver and is the most abundant protein in human blood plasma, comprising about 55% to 60% of total plasma protein by weight. It plays several critical roles: Osmotic regulation: Albumin contributes significantly to the oncotic pressure of blood, which helps maintain the balance of fluid distribution between the bloodstream and tissues. This osmotic pressure is crucial for preventing fluid leakage from blood vessels into surrounding tissues. Transportation: Albumin serves as a carrier protein, transporting various substances in the blood, including hormones, fatty acids, bilirubin, calcium, and drugs. By binding to these molecules, albumin helps solubilize them and transport them efficiently throughout the body. Buffering: Albumin acts as a buffer in the blood, helping to maintain pH balance by binding to acidic and basic compounds.Antioxidant: Albumin possesses antioxidant properties and plays a role in scavenging free radicals and protecting cells from oxidative damage.Because of its multiple functions, alterations in albumin levels can indicate various health conditions. Low albumin levels (hypoalbuminemia) can be seen in liver disease, kidney disease, malnutrition, inflammation, and certain chronic conditions. Conversely, high albumin levels (hyperalbuminemia) are less common but can occur in conditions such as dehydration or during recovery from burns.

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse,rat


immunogen target

albumin


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB, IHC


observerd MW

65 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:50 - 1:200; IHC: 1:50 - 1:500


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)


or code

ALB


alias

GIG20,GIG42


note

This product is for research use only.


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