anti- akt1 antibody

Este producto es parte de AKT1 - RAC-alpha serine/threonine-protein kinase 1
anti- akt1 antibody

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-AKT1

proveedor

FineTest

reference

FNab10227

Tested Applications

ELISA, WB, IHC

reactivity

human,rat

status

RUO

clonality

polyclonal

Background

The AKT (also known as Protein Kinase B) is a pivotal enzyme involved in regulating various cellular processes like metabolism, proliferation, survival, and growth. It acts downstream of phosphoinositide 3-kinase (PI3K) signaling pathway, which is activated by growth factors and cytokines. RAC-alpha serine/threonine-protein kinase is the full name of AKT. It belongs to the AGC (protein kinase A/protein kinase G/protein kinase C) family of kinases. AKT has three isoforms: AKT1, AKT2, and AKT3. Each isoform has slightly different tissue distributions and roles but shares the same basic structure and mechanism of action.Activation of AKT typically occurs through phosphorylation at two key residues: threonine 308 (Thr308) and serine 473 (Ser473). Once activated, AKT phosphorylates various downstream targets, including transcription factors, metabolic enzymes, and cell cycle regulators, ultimately leading to diverse cellular responses. Dysregulation of AKT signaling is implicated in various diseases, including cancer, diabetes, and cardiovascular diseases. Therefore, AKT has emerged as a significant target for therapeutic interventions in these conditions.

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,rat


immunogen target

RAC-alpha serine/threonine-protein kinase


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB, IHC


observerd MW

48/55 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:500-1:2000; IHC: 1:50-1:500


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

AKT1


alias

AKT1,PKB,RAC,RAC-ALPHA


note

This product is for research use only.


Quizá le pueda interesar

Human AKT1(RAC-alpha serine/threonine-protein kinase) ELISA Kit

Human AKT1(RAC-alpha serine/threonine-protein kinase) ELISA Kit

proveedor

FineTest

reference

EH0532

reactivity

human

status

RUO

Precio a consultar

Ver más

anti- AKT1 antibody

anti- AKT1 antibody

proveedor

FineTest

reference

FNab00268

Tested Applications

ELISA, WB, IHC, IF

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immo...

Precio a consultar

Ver más

anti- AKT1 antibody

anti- AKT1 antibody

proveedor

FineTest

reference

FNab00269

Tested Applications

ELISA, IHC, WB, IF

reactivity

human

status

RUO

clonality

polyclonal

AKT1 is one of 3 closely related serine/threonine-protein kinases(AKT1, AKT2 and AKT3) called the AKT kinase, and which ...

Precio a consultar

Ver más