proveedor
FineTestreference
FNab09944Tested Applications
ELISA, WBreactivity
human,mouse,ratstatus
RUOclonality
polyclonalDescripción
AIF1, also named as G1, IBA1 or daintain/AIF-1, is a 143 amino acid cytoplasmic, inflammation response scaffold protein. It is constitutively expressed in monocytes and macrophages and is known to be involved in macrophage activation. It is a marker of activated macrophage. Despite a lack of detailed knowledge on the in vivo physiological functions of AIF-1, there is growing evidence that shows its aberrant expression contributes to the pathogenesis of many autoimmune diseases, including rheumatoid arthritis. (20944424). AIF1 is an actin-binding protein that enhances membrane ruffling and RAC activation. It enhances lymphocyte migration and the actin-bundling activity of LCP1. AIF1 plays a role in RAC signaling and in phagocytosis and a role in vascular inflammation. AIF1 promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. It is also as a microglial cell marker.
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human,mouse,rat
immunogen target
allograft inflammatory factor 1
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB
observerd MW
16 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:500-1:2000
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
AIF1
alias
AIF 1, AIF1, G1, IBA1, IRT 1, Protein G1
uniprot id
https://www.uniprot.org/uniprotkb/P55008
gene id
https://www.ncbi.nlm.nih.gov/gene/199
note
This product is for research use only.
Quizá le pueda interesar
Human AIF1(Allograft inflammatory factor 1) ELISA Kit
proveedor
FineTestreference
EH1425reactivity
humanstatus
RUOPrecio a consultar
Ver másRat AIF-1(Allograft inflammatory factor 1) ELISA Kit
proveedor
FineTestreference
ER1595reactivity
ratstatus
RUOPrecio a consultar
Ver másanti- AIF1 antibody
proveedor
FineTestreference
FNab09944Tested Applications
ELISA, WBreactivity
human,mouse,ratstatus
RUOclonality
polyclonalAIF1, also named as G1, IBA1 or daintain/AIF-1, is a 143 amino acid cytoplasmic, inflammation response scaffold protein....
Precio a consultar
Ver más