ADRA2B antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
ADRA2B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab10774
tested applications
ELISA, IHC
Description
ADRA2B, also named as ADRA2L1 and ADRA2RL1, belongs to the G-protein coupled receptor 1 family. ADRA2B mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The antibody is specific to ADRA2B.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | adrenergic, alpha-2B-, receptor (ADRA2B) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P18089 |
| Gene ID | 151 |
| Alias | ADRA2B,ADRA2L1,ADRA2RL1,Adrenergic alpha2B- receptor class III,Adra-2b,alpha2B,ADRARL1, ALPHA2BAR, FAME2, alpha-2BAR |
| Background | Antibody anti-ADRA2B |
| Status | RUO |
| Note | Mol. Weight 49 kDa |
Descripción
The alpha-2 adrenergic receptors (ADRA2) are a class of G protein-coupled receptors (GPCRs) that respond to the neurotransmitter noradrenaline (norepinephrine) and play a role in regulating various physiological processes. There are three main subtypes of alpha-2 adrenergic receptors: Alpha-2A (ADRA2A), Alpha-2B (ADRA2B), and Alpha-2C (ADRA2C). ADRA2B receptors are found in various tissues, including vascular smooth muscle, the heart, and the pancreas. They are involved in the regulation of vascular tone, cardiac function, and insulin secretion. Activation of ADRA2B receptors leads to vasoconstriction, decreased heart rate, and inhibition of insulin release from pancreatic beta cells. ADRA2B receptors also play a role in modulating neurotransmitter release in the central nervous system.ADRA2C receptors are widely distributed in the central nervous system, as well as in peripheral tissues such as vascular smooth muscle and the heart. They play a role in regulating sympathetic nervous system activity, vascular tone, and cardiac function. Activation of ADRA2C receptors leads to vasoconstriction and decreased heart rate. ADRA2C receptors also modulate neurotransmitter release in the central nervous system.
Related Products
ADRA2B-Specific antibody
ADRA2B, also named as ADRA2L1 and ADRA2RL1, belongs to the G-protein coupled receptor 1 family. ADRA2B mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The antibody is specific to ADRA2B.
Ver ProductoADRA2B antibody
ADRA2B, also named as ADRA2L1 and ADRA2RL1, belongs to the G-protein coupled receptor 1 family. ADRA2B mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The antibody is specific to ADRA2B.
Ver Producto