ADRA2A antibody
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935106861
info@markelab.com
name
ADRA2A antibody
category
Primary Antibodies
provider
FineTest
reference
FNab10851
tested applications
ELISA, WB
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Alpha-2A adrenergic receptor (ADRA2A) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 50 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P08913 |
| Gene ID | 4313 |
| Alias | ADRA2A,ADRA2,ADRA2R,Adrenergic alpha 2A receptor ,Adra-2 ,Adra-2a,ALPHA2AAR, ZNF32 |
| Background | Antibody anti-ADRA2A |
| Status | RUO |
| Note | Mol. Weight 50 kDa |
The alpha-2 adrenergic receptors (ADRA2) are a class of G protein-coupled receptors (GPCRs) that respond to the neurotransmitter noradrenaline (norepinephrine) and play a role in regulating various physiological processes. There are three main subtypes of alpha-2 adrenergic receptors: Alpha-2A (ADRA2A), Alpha-2B (ADRA2B), and Alpha-2C (ADRA2C). ADRA2A receptors are primarily located in the central nervous system, including the brain and spinal cord. They are involved in the modulation of neurotransmitter release, particularly in the regulation of noradrenaline release. Activation of ADRA2A receptors inhibits the release of neurotransmitters such as noradrenaline, dopamine, and serotonin, leading to a decrease in sympathetic nervous system activity. ADRA2A receptors also play a role in regulating blood pressure, cognition, and mood.
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