anti- ADRA1B antibody

Este producto es parte de ADRA1 - Alpha-1A(1B) (1C) Adrenergic receptor
anti- ADRA1B antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-ADRA1B

proveedor

FineTest

reference

FNab00178

Tested Applications

ELISA, WB

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.


Background

The adrenergic receptors are a class of G protein-coupled receptors (GPCRs) that respond to the neurotransmitter adrenaline (epinephrine) and noradrenaline (norepinephrine). The alpha-1 adrenergic receptor (ADRA1) is one subtype of adrenergic receptors, and it has three main subtypes: Alpha-1A (ADRA1A), Alpha-1B (ADRA1B), and Alpha-1D (ADRA1D). ADRA1B encodes the α1B-adrenergic receptor, predominantly expressed in the liver, heart, and cerebral blood vessels.

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse,rat


immunogen target

adrenergic, alpha-1B-, receptor


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB


observerd MW

50 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:200-1:2000


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

ADRA1B


alias

ADRA1B,ADRA1,ALPHA1BAR,adrenergic alpha 1B receptor


note

This product is for research use only.


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