ADORA1 antibody

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935106861
info@markelab.com
name
ADORA1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00159
tested applications
ELISA, WB,IHC
Description
ADORA1, also named as RDC7, is a receptor for adenosine. It is mediated by G proteins which inhibit adenylyl cyclase. Adenosine is an important mediator of ethanol intoxication and exerts some of its effects via ADORA1 in the central nervous system. The antibody is specific to ADORA1.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | adenosine A1 receptor (ADORA1) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1:200-1:2000; IHC: 1:50-1:500 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 37 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB,IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | P30542 |
Gene ID | 134 |
Alias | ADORA1,RDC7 ,adenosine receptor A1,A1-AR,A1R, A1 receptor |
Background | Antibody anti-ADORA1 |
Status | RUO |
Note | Mol. Weight 37 kDa |
Descripción
Adenosine receptors are a class of G protein-coupled receptors (GPCRs) that respond to the endogenous nucleoside adenosine. They play essential roles in various physiological processes, including neurotransmission, vascular tone regulation, immune responses, and inflammation. A1 Receptor (ADORA1) is predominantly expressed in the brain, where it modulates neurotransmission, neuronal excitability, and synaptic plasticity. A1 receptors also regulate cardiovascular function, immune responses, and renal function.
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