Adenosine A1 Receptor (ADORA1) Antibody
292.5€ (80 µl)
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935106861
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name
Adenosine A1 Receptor (ADORA1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx028045
tested applications
ELISA, WB
Description
The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adenosine A1 Receptor (ADORA1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P30542 |
| Alias | ADORA1,RDC7 ,adenosine receptor A1,A1-AR,A1R, A1 receptor |
| Background | Antibody anti-ADORA1 |
| Status | RUO |
Descripción
Adenosine receptors are a class of G protein-coupled receptors (GPCRs) that respond to the endogenous nucleoside adenosine. They play essential roles in various physiological processes, including neurotransmission, vascular tone regulation, immune responses, and inflammation. A1 Receptor (ADORA1) is predominantly expressed in the brain, where it modulates neurotransmission, neuronal excitability, and synaptic plasticity. A1 receptors also regulate cardiovascular function, immune responses, and renal function.
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