Adenosine A1 Receptor (ADORA1) Antibody
Pida mas información
935106861
info@markelab.com
Precio
292.5€ (80 µl)
Antibody anti-ADORA1
proveedor
Abbexareference
abx028045Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5' UTR have been found for this gene.
Background
Adenosine receptors are a class of G protein-coupled receptors (GPCRs) that respond to the endogenous nucleoside adenosine. They play essential roles in various physiological processes, including neurotransmission, vascular tone regulation, immune responses, and inflammation. A1 Receptor (ADORA1) is predominantly expressed in the brain, where it modulates neurotransmission, neuronal excitability, and synaptic plasticity. A1 receptors also regulate cardiovascular function, immune responses, and renal function.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Adenosine A1 Receptor (ADORA1)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified through a protein A column, followed by peptide affinity purification.
recommended dilution
WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ADORA1
dry ice
No
availability
Shipped within 5-10 working days.
alias
ADORA1,RDC7 ,adenosine receptor A1,A1-AR,A1R, A1 receptor
uniprot id
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