ADCY3 antibody
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935106861
info@markelab.com
name
ADCY3 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00156
tested applications
ELISA, WB, IHC, IF
Description
AC3 is typically found at 130 kDa in olfactory tissues.In nonolfactory tissues (such as sperm), this protein is reported to migrate with a molecular mass of 55 kDa,occasionally accompanied by additional bands at either 90 or 130 kDa(PMID:9539154).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | adenylate cyclase 3 (ADCY3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:2000; IHC: 1:20-1:200; IP: 1:200-1:2000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 170-180 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O60266 |
| Gene ID | 109 |
| Alias | AC-III,AC3,BMIQ19,Adenylate cyclase type 3 |
| Background | Antibody anti-ADCY3 |
| Status | RUO |
| Note | Mol. Weight 170-180 kDa |
Descripción
ADCY3 is a key effector enzyme involved in the production of cAMP and is localized predominantly in the olfactory epithelium and brain regions. It mediates odorant signaling in olfactory sensory neurons, playing a critical role in the sense of smell. ADCY3 is activated by G-proteins and modulated by calcium ions. Beyond olfaction, ADCY3 is implicated in energy balance, glucose metabolism, and obesity, as its dysfunction has been linked to obesity and insulin resistance. It also participates in cellular signaling related to growth and development.
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