anti- ADCY3 antibody
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Precio
Precio a consultar
Antibody anti-ADCY3
proveedor
FineTestreference
FNab00156Tested Applications
ELISA, WB, IHC, IFreactivity
human,mouse,ratstatus
RUOclonality
polyclonalDescripción
AC3 is typically found at 130 kDa in olfactory tissues.In nonolfactory tissues (such as sperm), this protein is reported to migrate with a molecular mass of 55 kDa,occasionally accompanied by additional bands at either 90 or 130 kDa(PMID:9539154).
Background
ADCY3 is a key effector enzyme involved in the production of cAMP and is localized predominantly in the olfactory epithelium and brain regions. It mediates odorant signaling in olfactory sensory neurons, playing a critical role in the sense of smell. ADCY3 is activated by G-proteins and modulated by calcium ions. Beyond olfaction, ADCY3 is implicated in energy balance, glucose metabolism, and obesity, as its dysfunction has been linked to obesity and insulin resistance. It also participates in cellular signaling related to growth and development.
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human,mouse,rat
immunogen target
adenylate cyclase 3
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB, IHC, IF
observerd MW
170-180 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:200-1:2000; IHC: 1:20-1:200; IP: 1:200-1:2000; IF: 1:20-1:200
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
ADCY3
alias
AC-III,AC3,BMIQ19,Adenylate cyclase type 3
uniprot id
note
This product is for research use only.
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