anti- ADAM5 antibody

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935106861
info@markelab.com
name
anti- ADAM5 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00143
tested applications
ELISA, WB, IHC, IF
Description
This is a non catalytic metalloprotease-like protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | ADAM metallopeptidase domain 5 pseudogene |
Host | Rabbit |
Reactivity | human |
Recommended Dilution | WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 47 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q6NVV9 |
Gene ID | 255926 |
Alias | ADAM5P,TMDC2,Rich Protein II,TMDc II,ADAM-5 |
Background | Antibody anti-ADAM5 |
Status | RUO |
Note | This product is for research use only. |
Descripción
ADAM metallopeptidase domain 5 (ADAM5) is a gene that encodes a protein belonging to the ADAM (a disintegrin and metalloproteinase domain) family. This family of proteins plays various roles in cellular processes such as cell adhesion, migration, proteolysis, and signaling. ADAM5 specifically is involved in sperm function and fertilization.In humans, ADAM5 is predominantly expressed in the testis, where it plays a crucial role in sperm development and function. It is involved in processes such as sperm maturation, motility, and interaction with the egg during fertilization. Dysfunction or mutations in ADAM5 gene may lead to impaired sperm function, which can result in infertility or reproductive disorders.
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