anti- ACTR3B antibody

Name: anti- ACTR3B antibody
Brand: FineTest
SKU: FNab00127
Availability: OnlineOnly

Este producto es parte de ACTR - Actin related protein

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-ACTR3B

proveedor

FineTest

reference

FNab00127

Tested Applications

ELISA, WB

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor(NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors.

Background

ACTR3B is a paralog of ACTR3 but has specialized tissue-specific roles, particularly in the brain and immune system. Like ACTR3, it contributes to actin filament nucleation and remodeling as part of ARP2/3-like complexes. However, ACTR3B may have unique regulatory interactions, enabling fine-tuning of cytoskeletal dynamics in specific cellular environments. Its expression is critical for neuronal development and immune cell activation. Defects in ACTR3B have been associated with neurological impairments, suggesting its unique role in actin-mediated processes.

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

ARP3 actin-related protein 3 homolog B(yeast)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB

observerd MW

48 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500-1:5000

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

ACTR3B

alias

ACTR3B,ARP11,ARP3BETA

uniprot id

https://www.uniprot.org/uniprotkb/Q9P1U1

gene id

https://www.ncbi.nlm.nih.gov/gene/57180

note

This product is for research use only.

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