ACTR3B antibody
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Description
Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor(NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ARP3 actin-related protein 3 homolog B(yeast) (ACTR3B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 48 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9P1U1 |
| Gene ID | 57180 |
| Alias | ACTR3B,ARP11,ARP3BETA |
| Background | Antibody anti-ACTR3B |
| Status | RUO |
| Note | Mol. Weight 48 kDa |
Descripción
ACTR3B is a paralog of ACTR3 but has specialized tissue-specific roles, particularly in the brain and immune system. Like ACTR3, it contributes to actin filament nucleation and remodeling as part of ARP2/3-like complexes. However, ACTR3B may have unique regulatory interactions, enabling fine-tuning of cytoskeletal dynamics in specific cellular environments. Its expression is critical for neuronal development and immune cell activation. Defects in ACTR3B have been associated with neurological impairments, suggesting its unique role in actin-mediated processes.
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