Actin-Related Protein 3B (ACTR3B) Antibody
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935106861
info@markelab.com
Precio
292.5€ (80 µl)
Antibody anti-ACTR3B
proveedor
Abbexareference
abx033990Tested Applications
ELISA, WBreactivity
Human, Mousestatus
RUOclonality
PolyclonalDescripción
ACTR3B plays a role in the organization of the actin cytoskeleton. It may function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks and may decrease the metastatic potential of tumors.
Background
ACTR3B is a paralog of ACTR3 but has specialized tissue-specific roles, particularly in the brain and immune system. Like ACTR3, it contributes to actin filament nucleation and remodeling as part of ARP2/3-like complexes. However, ACTR3B may have unique regulatory interactions, enabling fine-tuning of cytoskeletal dynamics in specific cellular environments. Its expression is critical for neuronal development and immune cell activation. Defects in ACTR3B have been associated with neurological impairments, suggesting its unique role in actin-mediated processes.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse
immunogen target
Actin-Related Protein 3B (ACTR3B)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified through a protein A column, followed by peptide affinity purification.
recommended dilution
WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ACTR3B
dry ice
No
availability
Shipped within 5-10 working days.
alias
ACTR3B,ARP11,ARP3BETA
uniprot id
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Abbexareference
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ELISA, WBreactivity
Human, Mousestatus
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