ACTN3 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
ACTN3 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00122
tested applications
ELISA, WB
Description
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | actinin, alpha 3 (ACTN3) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:200-1:1000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 103 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q08043 |
| Gene ID | 89 |
| Alias | ACTN3D |
| Background | Antibody anti-ACTN3 |
| Status | RUO |
| Note | Mol. Weight 103 kDa |
Descripción
ACTN3 encodes alpha-actinin-3, a protein primarily expressed in fast-twitch skeletal muscle fibers, where it contributes to muscle strength and power. Unlike its closely related isoform ACTN2, ACTN3 is specialized for rapid and forceful contractions, playing a structural role in maintaining sarcomeric integrity and optimizing muscle performance. A common polymorphism in the ACTN3 gene results in the absence of alpha-actinin-3 in a significant proportion of the population, which has been associated with variations in muscle performance. The "null" variant is linked to reduced muscle power but enhanced endurance, reflecting its evolutionary role in adapting to physical demands. ACTN3 is crucial in regulating the balance between muscle power and endurance, with implications in athletic performance, muscle health, and susceptibility to muscle-related disorders.
Related Products
Human ACTN3 (Alpha-actinin-3) ELISA Kit
Ver Producto
ACTN3 antibody
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Ver ProductoACTN3 antibody
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Ver Producto