ACTL7A antibody
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Name
ACTL7A antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab00119
Tested Applications
ELISA, WB, IF
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | actin-like 7A (ACTL7A) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:2000; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 49 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9Y615 |
| Gene ID | 10881 |
| Alias | SPGF86 |
| Background | Antibody anti-ACTL7A |
| Status | RUO |
| Note | Mol. Weight 49 kDa |
Background
ACTL7A is a testis-specific actin-like protein predominantly expressed during spermatogenesis. It shares structural homology with canonical actins, including an ATP/ADP-binding site critical for nucleotide interactions. However, ACTL7A does not polymerize into filaments and instead performs unique roles in germ cell cytoskeletal dynamics. It is involved in chromatin remodeling during spermatid maturation, assisting in nuclear shaping and acrosome biogenesis. ACTL7A expression is tightly regulated, and disruptions in its function can lead to male infertility due to defects in sperm morphology and motility.
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