Actin Like 7A (ACTL7A) Antibody (Biotin)
169€ (20 µg)
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Name
Actin Like 7A (ACTL7A) Antibody (Biotin)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx105090
Tested Applications
ELISA
Description
Actin-like protein 7A Antibody (Biotin) is a Rabbit Polyclonal antibody against Actin-like protein 7A conjugated to Biotin.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Actin Like 7A (ACTL7A) Immunogen: Recombinant human Actin-like protein 7A protein (1-435AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y615 |
| Gene ID | 10881 |
| OMIM | 604303 |
| Alias | SPGF86 |
| Background | Antibody anti-ACTL7A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACTL7A is a testis-specific actin-like protein predominantly expressed during spermatogenesis. It shares structural homology with canonical actins, including an ATP/ADP-binding site critical for nucleotide interactions. However, ACTL7A does not polymerize into filaments and instead performs unique roles in germ cell cytoskeletal dynamics. It is involved in chromatin remodeling during spermatid maturation, assisting in nuclear shaping and acrosome biogenesis. ACTL7A expression is tightly regulated, and disruptions in its function can lead to male infertility due to defects in sperm morphology and motility.
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