ACSL5 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
ACSL5 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab00109
Tested Applications
ELISA, WB, IP
Description
Acyl-CoA synthetases(ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage(By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids(By similarity). It was suggested that it may also stimulate fatty acid oxidation(By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells.
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | acyl-CoA synthetase long-chain family member 5 (ACSL5) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 70 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9ULC5 |
| Gene ID | 51703 |
| Alias | ACS2,ACS5,DIAR13,FACL5 |
| Background | Antibody anti-ACSL5 |
| Status | RUO |
| Note | Mol. Weight 70 kDa |
Background
ACSL5 is a mitochondrial and cytosolic enzyme that activates long-chain fatty acids, particularly those with a preference for saturated and monounsaturated fatty acids, by converting them into acyl-CoA derivatives. ACSL5 is expressed in tissues like the small intestine, liver, and skeletal muscle, where it supports energy production, lipid absorption, and storage. This enzyme plays a crucial role in directing fatty acids toward oxidation or triglyceride synthesis, depending on metabolic demands, and is essential for maintaining energy homeostasis during fasting or high-fat diets. Dysregulation of ACSL5 has been implicated in metabolic disorders, such as obesity, diabetes, and non-alcoholic fatty liver disease, as altered fatty acid activation can lead to lipid accumulation and insulin resistance. ACSL5’s dual localization and specificity underscore its adaptability in regulating systemic and cellular lipid metabolism under diverse metabolic conditions.
Productos relacionados
Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody
ACSL5 Antibody is a Rabbit Polyclonal antibody against ACSL5. Acyl-CoA synthetase 5, a member of the ACSL gene family th…
Ver producto
Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody
Acyl-Coa Synthetase Long-Chain Family Member 5 Antibody is a Rabbit Polyclonal antibody against Acyl-Coa Synthetase Long…
Ver producto Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody
Rabbit Polyclonal against the ACSL5 protein.…
Ver producto