ACOT6 antibody
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935106861
info@markelab.com
name
ACOT6 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00092
tested applications
ELISA, WB, IHC
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | acyl-CoA thioesterase 6 (ACOT6) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 23 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q3I5F7 |
| Gene ID | 641372 |
| Alias | C14orf42,c14_5530 |
| Background | Antibody anti-ACOT6 |
| Status | RUO |
| Note | Mol. Weight 23 kDa |
ACOT6 is a peroxisomal enzyme that hydrolyzes short- and medium-chain acyl-CoA molecules into free fatty acids and CoA, playing a critical role in peroxisomal lipid metabolism and the detoxification of acyl-CoA intermediates. It is expressed in metabolically active tissues such as the liver and kidney, where it participates in the breakdown of branched-chain fatty acids and bile acid intermediates. By regulating acyl-CoA and CoA levels, ACOT6 prevents the accumulation of potentially toxic lipid intermediates while supporting peroxisomal β-oxidation and cellular lipid homeostasis. Dysregulation of ACOT6 has been associated with metabolic disorders, including fatty acid oxidation deficiencies and lipid storage diseases, where impaired lipid processing leads to cellular dysfunction. Its role in maintaining peroxisomal balance underscores its importance in systemic metabolic health and adaptability during periods of metabolic stress.
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