anti- ACBD5 antibody

Este producto es parte de ACBD - Acyl-CoA Binding Domain Containing
anti- ACBD5 antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-ACBD5

proveedor

FineTest

reference

FNab00076

Tested Applications

ELISA, WB

reactivity

human,mouse

status

RUO

clonality

polyclonal

Descripción

Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium-and long-chain acyl-CoA esters.


Background

ACBD5 is a peroxisomal protein that serves a key role in lipid metabolism by transporting very-long-chain fatty acyl-CoA into peroxisomes for beta-oxidation. It acts as a tether between peroxisomes and the endoplasmic reticulum (ER) by interacting with the ER-resident protein VAPB, enabling efficient lipid exchange between these organelles. ACBD5 is essential for maintaining peroxisomal function and lipid homeostasis, with significant implications for energy production and membrane lipid composition. Mutations in ACBD5 are associated with peroxisomal disorders, such as Zellweger spectrum disorders, which are characterized by defects in lipid metabolism. ACBD5 is also being studied for its potential role in modulating inflammation and oxidative stress in metabolic diseases.

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse


immunogen target

acyl-Coenzyme A binding domain containing 5


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB


observerd MW

65 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:200-1:2000


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

ACBD5


alias

RDLKD


note

This product is for research use only.


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