anti- ACBD5 antibody
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Precio
Precio a consultar
Antibody anti-ACBD5
proveedor
FineTestreference
FNab00076Tested Applications
ELISA, WBreactivity
human,mousestatus
RUOclonality
polyclonalDescripción
Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium-and long-chain acyl-CoA esters.
Background
ACBD5 is a peroxisomal protein that serves a key role in lipid metabolism by transporting very-long-chain fatty acyl-CoA into peroxisomes for beta-oxidation. It acts as a tether between peroxisomes and the endoplasmic reticulum (ER) by interacting with the ER-resident protein VAPB, enabling efficient lipid exchange between these organelles. ACBD5 is essential for maintaining peroxisomal function and lipid homeostasis, with significant implications for energy production and membrane lipid composition. Mutations in ACBD5 are associated with peroxisomal disorders, such as Zellweger spectrum disorders, which are characterized by defects in lipid metabolism. ACBD5 is also being studied for its potential role in modulating inflammation and oxidative stress in metabolic diseases.
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human,mouse
immunogen target
acyl-Coenzyme A binding domain containing 5
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB
observerd MW
65 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:200-1:2000
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
ACBD5
alias
RDLKD
uniprot id
note
This product is for research use only.
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