Acyl-CoA Binding Domain Containing 5 (ACBD5) Antibody
195€ (20 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Acyl-CoA Binding Domain Containing 5 (ACBD5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx125485
tested applications
ELISA, WB
Description
ACBD5 Antibody is a Rabbit Polyclonal against ACBD5.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Acyl-CoA Binding Domain Containing 5 (ACBD5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5T8D3 |
| Gene ID | 91452 |
| NCBI Accession | NP_663736.2 |
| Alias | RDLKD |
| Background | Antibody anti-ACBD5 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
ACBD5 is a peroxisomal protein that serves a key role in lipid metabolism by transporting very-long-chain fatty acyl-CoA into peroxisomes for beta-oxidation. It acts as a tether between peroxisomes and the endoplasmic reticulum (ER) by interacting with the ER-resident protein VAPB, enabling efficient lipid exchange between these organelles. ACBD5 is essential for maintaining peroxisomal function and lipid homeostasis, with significant implications for energy production and membrane lipid composition. Mutations in ACBD5 are associated with peroxisomal disorders, such as Zellweger spectrum disorders, which are characterized by defects in lipid metabolism. ACBD5 is also being studied for its potential role in modulating inflammation and oxidative stress in metabolic diseases.
Related Products
anti- ACBD5 antibody
Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium-and long-chain acyl-CoA esters.
Ver Producto
Acyl-CoA Binding Domain Containing 5 (ACBD5) Antibody
Rabbit Polyclonal against the ACBD5 protein.
Ver Producto
Acyl-CoA Binding Domain Containing 5 (ACBD5) Antibody
ACBD5 Antibody is a Rabbit Polyclonal against ACBD5.
Ver Producto