Acyl-CoA Binding Domain Containing 5 (ACBD5) Antibody
195€ (20 µl)
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Name
Acyl-CoA Binding Domain Containing 5 (ACBD5) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx125485
Tested Applications
ELISA, WB
Description
ACBD5 Antibody is a Rabbit Polyclonal against ACBD5.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Acyl-CoA Binding Domain Containing 5 (ACBD5) Immunogen: Recombinant protein corresponding to ACBD5. The exact sequence is proprietary. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 60 kDa Observed MW: 70 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5T8D3 |
| Gene ID | 91452 |
| NCBI Accession | NP_663736.2 |
| Alias | RDLKD |
| Background | Antibody anti-ACBD5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACBD5 is a peroxisomal protein that serves a key role in lipid metabolism by transporting very-long-chain fatty acyl-CoA into peroxisomes for beta-oxidation. It acts as a tether between peroxisomes and the endoplasmic reticulum (ER) by interacting with the ER-resident protein VAPB, enabling efficient lipid exchange between these organelles. ACBD5 is essential for maintaining peroxisomal function and lipid homeostasis, with significant implications for energy production and membrane lipid composition. Mutations in ACBD5 are associated with peroxisomal disorders, such as Zellweger spectrum disorders, which are characterized by defects in lipid metabolism. ACBD5 is also being studied for its potential role in modulating inflammation and oxidative stress in metabolic diseases.
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