Very long-chain acyl-CoA dehydrogenase (VLCAD) is one of four flavoproteins which catalyze the initial step of the mitochondrial b-oxidation spiral. It belongs to the acyl-CoA dehydrogenase family and is a homodimer of a 71-kDa polypeptide. The molecular mass of the nondenatured trypsinized VLCAD is 98 kDa, by gel filtration chromatography, indicating that it is a homodimer of the 48 kDa(tryptic digest) polypeptide(PMID:9461620). Defects in ACADVL are the cause of acyl-CoA dehydrogenase very long chain deficiency (ACADVLD). It has 2 isoforms(70 kDa and 68 kDa ) produced by alternative splicing and a transit peptide.
Primary Antibodies
polyclonal
human,mouse,rat
acyl-Coenzyme A dehydrogenase, very long chain
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IHC
48 kDa,68-73 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:200-1:2000; IHC: 1:20-1:200
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
ACADVL
ACAD6,LCACD,VLCAD
This product is for research use only.
Very long-chain acyl-CoA dehydrogenase (VLCAD) is one of four flavoproteins which catalyze the initial step of the mitoc...
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225€ (2 µg)
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