ALOX15B antibody

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935106861
info@markelab.com
name
ALOX15B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00005
tested applications
ELISA, WB, IHC,IF
Description
In humans, there are 6 functional lipoxygenases genes. Two of them encode for arachidonic acid 12-lipoxygenating(ALOX12, ALOX12B) and two for 15-lipoxygenating enzymes(ALOX15, ALOX15B). ALOX15B has been described as the most abundant 15-lipoxygenating enzyme species in human carotid atherosclerotic lesions and to be associated with cerebrovascular symptoms.(PMID:24373925). ALOX15B has 4 isoforms produced by alternative splicing with the MW of 76, 67, 69 and 73 kDa.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | arachidonate 15-lipoxygenase, type B (ALOX15B) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:200-1:2000; IHC: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 76 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC,IF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | O15296 |
Alias | 15-lipoxygenase 2,Arachidonate 15-lipoxygenase B |
Background | Antibody anti-ALOX15B |
Status | RUO |
Note | Mol. Weight 76 kDa |
Descripción
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ALOX15B antibody
In humans, there are 6 functional lipoxygenases genes. Two of them encode for arachidonic acid 12-lipoxygenating(ALOX12, ALOX12B) and two for 15-lipoxygenating enzymes(ALOX15, ALOX15B). ALOX15B has been described as the most abundant 15-lipoxygenating enzyme species in human carotid atherosclerotic lesions and to be associated with cerebrovascular symptoms.(PMID:24373925). ALOX15B has 4 isoforms produced by alternative splicing with the MW of 76, 67, 69 and 73 kDa.
Ver Producto