Anterior Gradient Protein 2 (AGR2) Antibody
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935106861
info@markelab.com
Precio
416€ (200 µl)
Antibody anti-AGR2
proveedor
Abbexareference
abx431775Tested Applications
P-ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
AGR2 Antibody is a Goat Polyclonal antibody against AGR2.
Background
AGR2 is a protein involved in the endoplasmic reticulum (ER) stress response and functions as a protein disulfide isomerase (PDI), facilitating the proper folding of secreted and membrane proteins. It is primarily expressed in secretory tissues such as the gastrointestinal tract, lungs, and prostate, where it maintains ER homeostasis by catalyzing the formation of disulfide bonds in proteins. AGR2 also plays a role in cell adhesion and migration, partly through its interaction with mucins like MUC1 and MUC2. Overexpression of AGR2 is frequently observed in cancers, including breast, pancreatic, and prostate cancers, where it contributes to tumor progression, chemoresistance, and metastasis by promoting cell survival under stress conditions
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Anterior Gradient Protein 2 (AGR2)
host
Goat
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
P-ELISA, WB
purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
recommended dilution
P-ELISA: 1/16000. Optimal dilutions/concentrations should be determined by the end user.
buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
size 1
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
AGR2
dry ice
No
availability
Shipped within 5-10 working days.
alias
AG-2,AG2,GOB-4,HAG-2,HEL-S-116,HPC8
NCBI accession
NP_006399.1
note
Concentration: 0.5 mg/ml -
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