Anoctamin-7 (ANO7) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Anoctamin-7 (ANO7) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx034367
tested applications
ELISA, WB
Description
ANO7 may act as a calcium-activated chloride channel. This protein May play a role in cell-cell interactions.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Anoctamin-7 (ANO7) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6IWH7 |
| Alias | ANO7,NGEP,PCANAP5,TMEM16G |
| Background | Antibody anti-ANO7 |
| Status | RUO |
Descripción
ANO7, also known as TMEM16G, is a member of the anoctamin family of proteins with roles in calcium-activated ion transport and cell adhesion. ANO7 is highly expressed in the prostate gland, where it is involved in the regulation of prostate epithelial cell function and contributes to cellular growth and adhesion. Due to its tissue-specific expression, ANO7 has been studied as a biomarker for prostate cancer, where it is overexpressed in certain tumor types and may influence cancer progression, metastasis, and patient prognosis. Mutations in ANO7 have also been associated with increased susceptibility to prostate cancer. Its dual role in ion transport and cell-cell interactions highlights its functional significance in prostate physiology and pathology.
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