Anoctamin 4 (ANO4) Antibody (Biotin)
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935106861
info@markelab.com
Precio
162.5€ (20 µg)
Antibody anti-ANO4
proveedor
Abbexareference
abx307174Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
ANO4 Antibody (Biotin) is a Rabbit Polyclonal against ANO4 conjugated to Biotin.
Background
ANO4, also known as TMEM16D, is a member of the anoctamin family of calcium-activated chloride channels (CaCCs) and phospholipid scramblases. ANO4 is predominantly expressed in the nervous system, including the brain, where it regulates neuronal excitability and calcium signaling. It is believed to play a role in modulating synaptic transmission and neuronal activity, particularly in pathways controlling motor coordination and cognitive functions. Dysregulation of ANO4 has been associated with neurological disorders, such as movement abnormalities and neurodegenerative diseases, due to its role in maintaining proper neuronal signaling. Emerging evidence also suggests a role for ANO4 in cell proliferation and cancer progression, where altered calcium homeostasis and ion transport contribute to tumor development.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Anoctamin 4 (ANO4)
host
Rabbit
conjugation
Biotin
form
Liquid
tested applications
ELISA
purity
> 95%
purification
Purified by Protein G.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
or code
ANO4
dry ice
No
availability
Shipped within 5-10 working days.
alias
ANO4,TMEM16D
uniprot id
NCBI accession
NP_001273544.1, NM_001286615.1
note
This product is for research use only.
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