Anoctamin 4 (ANO4) Antibody (Biotin)
169€ (20 µg)
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name
Anoctamin 4 (ANO4) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx307174
tested applications
ELISA
Description
ANO4 Antibody (Biotin) is a Rabbit Polyclonal against ANO4 conjugated to Biotin.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Anoctamin 4 (ANO4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q32M45 |
| Gene ID | 121601 |
| NCBI Accession | NP_001273544.1, NM_001286615.1 |
| OMIM | 610111 |
| Alias | ANO4,TMEM16D |
| Background | Antibody anti-ANO4 |
| Status | RUO |
Descripción
ANO4, also known as TMEM16D, is a member of the anoctamin family of calcium-activated chloride channels (CaCCs) and phospholipid scramblases. ANO4 is predominantly expressed in the nervous system, including the brain, where it regulates neuronal excitability and calcium signaling. It is believed to play a role in modulating synaptic transmission and neuronal activity, particularly in pathways controlling motor coordination and cognitive functions. Dysregulation of ANO4 has been associated with neurological disorders, such as movement abnormalities and neurodegenerative diseases, due to its role in maintaining proper neuronal signaling. Emerging evidence also suggests a role for ANO4 in cell proliferation and cancer progression, where altered calcium homeostasis and ion transport contribute to tumor development.
Related Products
Anoctamin 4 (ANO4) Antibody (HRP)
ANO4 Antibody (HRP) is a Rabbit Polyclonal against ANO4 conjugated to HRP.
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