Anoctamin-4 (ANO4) Antibody
357.5€ (100 µg)
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935106861
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name
Anoctamin-4 (ANO4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx037157
tested applications
ELISA, WB
Description
Rabbit Polyclonal against the ANO4 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Anoctamin-4 (ANO4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ANO4,TMEM16D |
| Background | Antibody anti-ANO4 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
ANO4, also known as TMEM16D, is a member of the anoctamin family of calcium-activated chloride channels (CaCCs) and phospholipid scramblases. ANO4 is predominantly expressed in the nervous system, including the brain, where it regulates neuronal excitability and calcium signaling. It is believed to play a role in modulating synaptic transmission and neuronal activity, particularly in pathways controlling motor coordination and cognitive functions. Dysregulation of ANO4 has been associated with neurological disorders, such as movement abnormalities and neurodegenerative diseases, due to its role in maintaining proper neuronal signaling. Emerging evidence also suggests a role for ANO4 in cell proliferation and cancer progression, where altered calcium homeostasis and ion transport contribute to tumor development.
Related Products
Anoctamin 4 (ANO4) Antibody (HRP)
ANO4 Antibody (HRP) is a Rabbit Polyclonal against ANO4 conjugated to HRP.
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