Annexin A5 (ANXA5) Antibody (Biotin)
169€ (20 µg)
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name
Annexin A5 (ANXA5) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx105146
tested applications
ELISA
Description
Annexin V Antibody (Biotin) is a Rabbit Polyclonal antibody against Annexin V conjugated to Biotin. Recombinant Human Annexin V Protein (2-320Aa) This Protein Is An Anticoagulant Protein That Acts As An Indirect Inhibitor Of The Thromboplastin-Specific Complex, Which Is Involved In The Blood Coagulation Cascade.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Annexin A5 (ANXA5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P08758 |
| Gene ID | 308 |
| OMIM | 131230 |
| Alias | ANXA5,ANX5,ENX2,PP4 |
| Background | Antibody anti-ANXA5 |
| Status | RUO |
Descripción
ANXA5 is a well-known calcium- and phospholipid-binding protein involved in apoptosis, membrane repair, and anti-inflammatory processes. It binds to phosphatidylserine (PS), a phospholipid exposed on the outer leaflet of apoptotic cells, making ANXA5 a widely used marker for apoptosis detection. ANXA5 regulates coagulation and fibrinolysis by preventing the assembly of coagulation complexes on cell membranes, contributing to antithrombotic activity. It is expressed in various tissues, including the placenta, where it plays roles in trophoblast function and pregnancy maintenance. Dysregulation of ANXA5 has been associated with autoimmune diseases, recurrent pregnancy loss, and cancers. Its apoptotic and anticoagulant properties make it a key protein in cellular homeostasis and disease pathology.
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