Annexin A13 (ANXA13) Antibody
292.5€ (80 µl)
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name
Annexin A13 (ANXA13) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx031063
tested applications
ELISA, WB
Description
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Annexin A13 (ANXA13) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P27216 |
| Alias | Annexin XIII,Annexin-13 |
| Background | Antibody anti-ANXA13 |
| Status | RUO |
Descripción
ANXA13 is considered the most ancestral member of the annexin family, serving as the evolutionary origin for annexin gene expansion. It is primarily expressed in the gastrointestinal tract and has been linked to processes such as membrane trafficking and intracellular signaling. ANXA13 plays a role in epithelial cell polarity and vesicular transport, particularly in the intestine, where it regulates mucosal homeostasis. Dysregulation of ANXA13 has been observed in gastrointestinal cancers, where it may influence tumor cell migration and invasion. Its function in maintaining epithelial integrity and its role in cancer progression highlight its importance in gastrointestinal biology and pathology.
