Annexin A11 (ANXA11) Antibody
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935106861
info@markelab.com
Precio
195€ (20 µl)
Antibody anti-ANXA11
proveedor
Abbexareference
abx006942Tested Applications
ELISA, WB, IF/ICC, IPreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
ANXA11 Antibody is a Rabbit Polyclonal Antibody against ANXA11.
Background
ANXA11 is a multifunctional protein involved in calcium signaling, RNA transport, and cell cycle regulation. It plays an important role in nuclear-cytoplasmic transport by binding RNA and contributing to the assembly of RNA granules. ANXA11 is also critical for cytokinesis, ensuring proper cell division by localizing to the midbody during the final stages of mitosis. Mutations in ANXA11 have been linked to amyotrophic lateral sclerosis (ALS), where defects in RNA transport and protein aggregation contribute to neurodegeneration. Dysregulation of ANXA11 has also been implicated in autoimmune diseases and cancer progression. Its diverse roles in RNA metabolism, calcium signaling, and cytokinesis make ANXA11 essential for cellular homeostasis and division.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
Annexin A11 (ANXA11)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IF/ICC, IP
purification
Purified by affinity chromatography.
recommended dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
size 1
20 µl
size 2
100 µl
size 3
2 × 100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ANXA11
dry ice
No
availability
Shipped within 5-10 working days.
alias
ANXA11,ANX11,Annexin XI
uniprot id
NCBI accession
NP_001148.1
note
Concentration: > 0.2 mg/ml -
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