Ankyrin Repeat Domain-Containing Protein 5 (ANKRD5) Antibody

Background

ANKRD5 (ANKEF1) is a unique protein containing both ankyrin repeat domains and an EF-hand domain, which suggests dual roles in protein-protein interactions and calcium-binding activity. The EF-hand domain indicates that ANKRD5 may play a role in calcium signaling, a critical process for cellular functions such as muscle contraction, signal transduction, and enzyme regulation. ANKRD5 likely acts as a scaffold protein that integrates calcium signaling with protein interactions to regulate cellular responses to stimuli. Its role in calcium-dependent pathways positions it as a significant factor in processes such as cellular stress adaptation, differentiation, and signal modulation. Dysregulation of ANKRD5 may contribute to disorders involving calcium imbalance, such as neurodegeneration or cardiovascular diseases.