Ankyrin Repeat Domain 26 (ANKRD26) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Ankyrin Repeat Domain 26 (ANKRD26) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx323091
tested applications
ELISA, IHC
Description
ANKRD26 Antibody is a Rabbit Polyclonal against ANKRD26.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ankyrin Repeat Domain 26 (ANKRD26) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/5000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UPS8 |
| Gene ID | 22852 |
| Alias | ANKRD26,KIAA1074,THC2 |
| Background | Antibody anti-ANKRD26 |
| Status | RUO |
Descripción
ANKRD26 is a protein with ankyrin repeat domains that plays a role in hematopoiesis, the process of blood cell production. ANKRD26 is expressed in hematopoietic stem cells and progenitors, where it regulates cellular proliferation, differentiation, and survival. Mutations in ANKRD26 are associated with familial thrombocytopenia (THC2), a rare genetic disorder characterized by low platelet counts and an increased risk of myeloid malignancies such as acute myeloid leukemia (AML). ANKRD26 is believed to influence transcriptional regulation and cell signaling pathways that control blood cell development and homeostasis. Its dysregulation disrupts normal hematopoiesis, contributing to abnormal cell growth and blood disorders, making it a critical factor for maintaining proper hematopoietic function.
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