935106861
info@markelab.com
Precio
43.75€ (10 µg)
AGTRL1 Antibody is a Rabbit Polyclonal antibody against AGTRL1.
AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.
Primary Antibodies
Polyclonal
Human
Angiotensin Receptor-Like 1 (AGTRL1)
Rabbit
Unconjugated
Liquid
WB, IF/ICC
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
10 µg
100 µg
200 µg
300 µg
1 mg
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
AGTR1
No
Shipped within 5-10 working days.
AGTR1,AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R,angiotensin II type-1 receptor
This product is for research use only.
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