Angiotensin II Receptor type 1, AT1, ATE. Peptide

Product specifications

Proteins and Peptides

Angiotensin II Receptor type 1 (181 187), AT1, ATE.

Unconjugated

Molecular Weight: 880.92 Da
Sequence Fragment: 181-187 AA

> 95% (HPLC)

5 mg

10 mg

25 mg

Lyophilized 

Not applicable.

Shipped within 10-20 working days.

Store dry at -20 °C. Avoid repeated freeze/thaw cycles.

No

AGTR1,AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R,angiotensin II type-1 receptor

Protein AGTR1

RUO

This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

AGTR1 is a G-protein-coupled receptor (GPCR) that mediates the majority of the physiological effects of angiotensin II, a key hormone in the renin-angiotensin-aldosterone system (RAAS). It is primarily expressed in tissues such as the heart, kidneys, vascular smooth muscle, and adrenal glands, where it regulates critical functions including blood pressure, fluid balance, and vascular tone. Upon activation by angiotensin II, AGTR1 initiates signaling cascades involving Gq proteins, which increase intracellular calcium levels and activate pathways such as protein kinase C (PKC), mitogen-activated protein kinase (MAPK), and reactive oxygen species (ROS) generation.

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