Angiopoietin-Related Protein 2 (ANGPTL2) Antibody (HRP)
169€ (20 µg)
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935106861
info@markelab.com
name
Angiopoietin-Related Protein 2 (ANGPTL2) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx312179
tested applications
ELISA
Description
ANGPTL2 Antibody (HRP) is a Rabbit Polyclonal against ANGPTL2 conjugated to HRP.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Angiopoietin-Related Protein 2 (ANGPTL2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UKU9 |
| Gene ID | 23452 |
| NCBI Accession | NP_036230.1, NM_012098.2 |
| OMIM | 605001 |
| Alias | ARP2,HARP |
| Background | Antibody anti-ANGPTL2 |
| Status | RUO |
Descripción
ANGPTL2 is a secreted glycoprotein that belongs to the angiopoietin-like (ANGPTL) protein family and plays critical roles in inflammation, angiogenesis, and tissue remodeling. ANGPTL2 promotes endothelial cell activation, migration, and vascular permeability, facilitating angiogenesis during wound healing and tissue repair. However, persistent overexpression of ANGPTL2 leads to chronic inflammation and tissue damage, contributing to the development of metabolic disorders, such as obesity and insulin resistance, as well as cardiovascular diseases. ANGPTL2 also enhances cancer progression by promoting tumor angiogenesis, metastasis, and epithelial-mesenchymal transition (EMT). Elevated ANGPTL2 levels are observed in various cancers, including breast, lung, and colorectal cancers, where its activity correlates with poor prognosis. It serves as a biomarker for inflammatory and tumor-associated conditions, linking inflammation to disease pathology. ANGPTL2’s dual role in tissue regeneration and chronic inflammation highlights its significance as a potential therapeutic target in cancer, cardiovascular diseases, and inflammatory disorders.
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