Androgen Receptor (AR) Antibody Pair
1430€ (5 × 96 tests)
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name
Androgen Receptor (AR) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx370008
tested applications
ELISA
Description
Androgen Receptor (AR) Antibody Pair for use in Sandwich ELISA assay development.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Antibody Pairs |
| Immunogen Target | Androgen Receptor (AR) |
| Reactivity | Rat |
| Assay Data | Detection Antibody Biotinilated |
| Assay Type | Sandwich |
| Recommended Dilution | Dilute the Capture Antibody 125-fold with Coating Buffer. Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent. Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 5 × 96 tests |
| Size 2 | 10 × 96 tests |
| Form | Standard: Lyophilized--Liquid (Capture Antibody and Detection Antibody) Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user. |
| Tested Applications | ELISA |
| Buffer | The Capture and Detection Antibody both contain 0.1% sodium azide. |
| Availability | Shipped within 5-20 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | KD,AIS,AR8,TFM,DHTR,SBMA,HYSP1,NR3C4,SMAX1,HUMARA,Dihydrotestosterone receptor,Nuclear receptor subfamily 3 group C member 4 |
| Background | Antibody Pair for AR |
| Status | RUO |
| Note | This antibody pair contains ( 5 x 96 det): Detection: 50 µg Capture: 200 µg Standard: 2 µg This product is for research use only. |
Descripción
Androgen receptor (AR) is a nuclear receptor that mediates the effects of androgens, the male sex hormones, by regulating gene expression AR plays a critical role in the development and maintenance of male sexual characteristics, as well as in the regulation of muscle mass, bone density, and red blood cell production It functions by binding to androgen hormones, such as testosterone, and translocating into the nucleus, where it interacts with DNA to regulate the transcription of target genes involved in cell growth, differentiation, and metabolism AR is essential for normal male development, including the formation of the male reproductive organs and secondary sexual characteristics During adulthood, AR helps maintain prostate function, muscle mass, and bone density Mutations in the AR gene can lead to a variety of disorders, including androgen insensitivity syndrome, prostate cancer, and certain types of hair loss, where abnormal AR signaling contributes to disease development AR is also a therapeutic target for androgen-related diseases, including prostate cancer, where therapies aim to block or modulate AR activity
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